˙OPTIMIZED TRYPTOPHAN PLUS 90 veg. capsules (30 servings 1000mg)

˙OPTIMIZED TRYPTOPHAN PLUS 90 veg. capsules (30 servings 1000mg)

Sale price $18.85 Regular price $31.99

*Promotes sleep (take 30-60 min. before sleep).

Serotonin support. May help balance mood, especially if depleted.

30 servings x 1000mg Tryptophan per container

Serotonin is a neurotransmitter in the brain associated with positive moods and restful sleep.1-4 To produce and maintain optimum serotonin levels, your body requires tryptophan, an essential amino acid the body can’t produce.1

In the body, tryptophan has been shown to improve sleep,3,4 enhance mood,1,2,4 and modulate stress.5 So Life Extension offers Optimized Tryptophan Plus to broadly and powerfully support tryptophan levels already within the normal range.

The basis for this formula is premium L-tryptophan, which has undergone significantly more rigorous manufacturing processes than regular tryptophan material to assure the highest purity and safety.

In addition to an optimum amount of premium tryptophan … this formula also provides a unique, balanced supply of other nutrients found to help maintain tryptophan activity in the body.6-8 Those nutrients include lysine, niacinamide, and extracts of hops and rosemary to provide nutritive support for the body’s production of serotonin.



Supplement Facts

Serving Size 3 vegetarian capsules*

Servings Per Container 30

Amount Per Serving*

Niacin (as niacinamide)

66 mg


1000 mg

L-Lysine (as L-Lysine HCl)

250 mg

Proprietary Tryptophan Plus Blend

285 mg

Perluxan® Hops standardized extract (cones), Ursole™ Rosemary standardized extract (leaf)

Other ingredients: vegetable cellulose (capsule), maltodextrin, modified food starch, hydroxypropyl methylcellulose, microcrystalline cellulose, stearic acid, silica.


Perluxan® is used by permission. 

Ursole™ is a trademark of Vitiva d. d., Slovenia.

Dosage and Use

  • Take up to three (3) capsules all at once before bedtime, or one capsule on an empty stomach before each meal, or as recommended by a healthcare practitioner.
  • For maximum absorption take with a small amount of carbohydrate, such as diluted juice.
  • Best if taken separately from protein or amino acids.


Serotonin syndrome is characterized by high levels of serotonin and symptoms like confusion, sweating, agitation, nausea, involuntary muscle contractions, and racing heartbeat. Do not take L-tryptophan if you experience these symptoms. Because tryptophan may have numerous drug interactions (most commonly, MAOIs and SSRIs) consult your healthcare provider before taking this product if you are taking prescription medications. Do not use before driving or operating heavy machinery.


  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.






  1. Int J Neurosci. 1992 Nov-Dec;67(1-4):127-44. 
  2. Curr Opin Neurobiol. 2013 Feb 2. pii: S0959-4388(13)00027-5. 
  3. Prog Neurobiol. 2000 Jan;60(1):13-35. 
  4. J Nutr. 2012 Dec;142(12):2236S-2244S. 
  5. J Exp Biol. 2002 Dec;205(Pt 23):3679-87. 
  6. Available at: http://www.tamu.edu/faculty/bmiles/lectures/ amcat.pdf. Accessed February 14, 2013. 
  7. Amino Acids. 2012 June 8. 
  8. J Clin Invest. 1999 April 15;103(8):1169–78.

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