Articles/NEWS

MTHFR debunked

MTHFR debunked

This fascinating article explains in detail many of the wrong assumptions of the so-called MTHFR-experts. It shows why some of their assumptions are based on facts almost pulled out of thin air. And it raises the question of how they can be sure about suggesting supplements based on single mutations. We look at the science behind it. One assumption among "MTHFR-experts" is that homozygous mutation in MTHFR C677T results in enzyme activity reduction of 70%. This exact number is far from proven. Besides, the very uncertain underlying scientific findings of activity reduction is even misinterpreted to the claim that 70% less...

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Human Study Confirms Potent Antidepressant Effects of SAM-e

Read this interesting study on how SAMe has improved the lives of those showing resistance to antidepressants (From LifeExtension®*): Human Study Confirms Potent Antidepressant Effects of SAM-e Life Extension® introduced SAMe (S-Adenosyl-Methionine) in 1997. Back then it was enormously popular in Europe, but unknown in the United States.  The National Institute of Mental Health decided to fund a double-blind, placebo-controlled trial that would evaluate SAMe as an additive therapy in those suffering major depression who were resistant to FDA-approved drugs.  Researchers at Harvard Medical School and Massachusetts General Hospital gave patients 800mg of SAMe twice daily along with a selective serotonin...

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Difference undermethylated vs. overmethylated (symptoms)

Difference undermethylated vs. overmethylated (symptoms)

According to Walsh Research Institute, nutritive support for treating underlying imbalances can be at least as effective for treating anxiety and depression as drugs (and without the side effects). As many as 85% with depression and 75% with anxiety in their massive database has reported significant improvement(1).Both for nutritive support and drugs, it is important to know about the underlying imbalance. Here is a comparison of undermethylated vs. over-methylated people to give you an idea of in which category you are. If you have some/more of the undermethylation symptoms and none/few of the over-methylation symptoms you are most likely in the...

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Methylfolate - the "suicidal" nutrient (don't believe the hype)

Large doses of methylfolate should be avoided for undermethylated depressives (it will make depression worse), only a small dose is beneficial when you are undermethylated (we all need some folate, but too much can make you feel worse). High doses of L-methylfolate (or folic acid) should only be given to overmethylated people with low folate. L-methylfolate is claimed to be a more bioavailable form than folic acid, so large doses of folic acid might not be absorbed in once. For instance, the Deplin brand of l-methylfolate is used in the following situations: In people with a major depressive disorder who have folate deficiency. Deplin...

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Why not only SAM-e?

Why not only SAM-e?

Most under-methylators are low in "everything" (homocysteine, SAMe, methionine, B6, Calcium, Magnesium, Zinc, Glutathione, Creatine, etc.) and what they need is more methyl. VITAcure Methyl Plus contains "everything" except SAM-e. An exception to this is folate: folate is essential in the methylation cycle*, but under-methylators are often too high in folate, and folate tends to accumulate and trap methyl, so avoid supplementation of high dose (but some is eventually necessary)! Initially, homocysteine is TOO LOW with under-methylators. That could cause some problems since SAM-e converts from Methionine in our cells, which again converts from homocysteine. When there is not enough homocysteine,...

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How do you know if you are undermethylated?

Just because you have an MTHFR C677T/A1298C mutation doesn’t mean you’re over or under methylated (although it would be one factor that might push the balance to undermethylation). Dr. Walsh (Walsh Research Institute) describes one’s methylation status as being like a tug of war between opposing factors. Many of those are genetic, and some are nutritional or environmental. According to Dr. Walsh’s research(1), 70% of the population are normal methylators, 22% are under-methylators, and 8% are over-methylators, but this again may depend on what you define as under/over-methylation/normal. Pfeiffer statistic says 45% are under-methylators and 15% are over-methylators (only 40% normal)....

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The new product: VITAcure® Methyl Plus™ is now in stock

The new product: VITAcure® Methyl Plus™ is now in stock

February 2017: Finally our new and unique product: VITAcure Methyl Plus™ is in stock here in the US (Massachusetts) ready to be shipped today both within the US and to the rest of the world. VITAcure METHYL PLUS is a specially tailored product for people who are undermethylated. To increase methylation, one might also want to take SAM-e. It is essential to take cofactors in addition to the methyl-donator SAM-e to get the methionine-cycle functioning as it should. Before this supplement was available, one would have to source a number of different nutrients in addition to SAM-e, but finally, there is one product that covers almost...

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